A Viscous Protein Obtained in Large Amount from the Serum of a Patient with Multiple Myeloma.
نویسندگان
چکیده
A case of multiple myeloma with hyperproteinemia has recently been observed in which there was obtained, by prolonged dialysis of the blood plasma against distilled water, a large quantity of viscous protein. The excessive quantity of this protein, and the absence of reports of a similar observation in multiple myeloma, with the exception which will be discussed below, makes a record of the circumstances under which it was obtained of interest.
منابع مشابه
Characteristics of Potential Protein Biomarkers Extracted with 10% TCA from Blood Serum of Non-Hodgkin’s Lymphoma and Multiple Myeloma Patients
Blood serum has been extensively explored as a source of the bio-markers [1, 2]. For concentration of minor protein(s) and depletion of abundant blood serum proteins a 2,2,2-trichloroacetic acid (TCA) precipitation procedure is frequently applied [3]. However, a significant amount of proteins may be present in the TCA extracts, and these proteins are often not studied.Recently, we have sh...
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ورودعنوان ژورنال:
- The Journal of clinical investigation
دوره 22 2 شماره
صفحات -
تاریخ انتشار 1943